Publications
1155. Coadministration of Intranasal M2SR (M2-deficient Single Replication) Investigational Influenza Vaccine with Fluzone High Dose Induces Superior Immune Responses to Fluzone High Dose Alone in 65-85 Year Old Adults
Open Forum Infect Dis
Published December 2023 by Dr Bryan Murray
Development and usability testing of an electronic patient-reported outcome (ePRO) solution for patients with inflammatory diseases in an Advanced Therapy Medicinal Product (ATMP) basket trial
Journal of Patient-Reported Outcomes
Published October 2023 by Prof Alan Boyd
Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) results in clinical benefits and stabilization or slowing of disease progression in patients with Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial
Molecular Genetics and Metabolism Reports
Published September 2023 by Dr Bryan Murray and Dr Bryan Hurst
Immunotherapy with CD25/CD71-allodepleted T cells to improve T-cell reconstitution after matched unrelated donor hematopoietic stem cell transplant: a randomized trial
Published January 2023 by Kim Champion
Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial
The Lancet Oncology
Published November 2022 by Prof Alan Boyd
A novel maturity index for assessing medical device startups
Journal of Clinical and Translational Science
Published August 2022 by Katy Rudnick
Prevention of Respiratory Syncytial Virus Infection in Healthy Adults by a Single Immunization of Ad26.RSV.preF in a Human Challenge Study
The Journal of Infectious Diseases
Published August 2022 by Dr Bryan Murray
Safety and Antiviral Effects of Nebulized PC786 in a Respiratory Syncytial Virus Challenge Study
The Journal of Infectious Diseases
Published June 2022 by Dr Bryan Murray
Antiadenovirus Antibodies Predict Response Durability to Nadofaragene Firadenovec Therapy in BCG-unresponsive Non-muscle-invasive Bladder Cancer: Secondary Analysis of a Phase 3 Clinical Trial
European Urology
Published March 2022 by Prof Alan Boyd
EDP-938, a Respiratory Syncytial Virus Inhibitor, in a Human Virus Challenge
The New England Journal of Medicine
Published February 2022 by Dr Bryan Murray
PD09-02 ANTI-ADENOVIRAL ANTIBODY LEVELS PREDICT NADOFARAGENE FIRADENOVEC RESPONSE IN BCG-UNRESPONSIVE NMIBC: RESULTS FROM A PHASE 3 TRIAL
The Journal of Urology
Published September 2021 by Prof Alan Boyd
Process analysis of pluripotent stem cell differentiation to megakaryocytes to make platelets applying European GMP
NPJ Regenerative Medicine
Published May 2021 by Monica Pianella
Commentary on “Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model”
British Journal of Clinical Pharmacology
Published March 2021 by Prof Alan Boyd
Update on phase I study to evaluate the single- and multiple-dose pharmacokinetics of intravenous hydroxypropyl betacyclodextrin (HPβCD) in patients with Niemann-Pick disease type C (NPC-1) and the effects of dosing upon biomarkers of NPC disease
Molecular Genetics and Metabolism
Published February 2021 by Prof Alan Boyd
Update on safety and efficacy results for phase I/II trial of hydroxypropyl betacyclodextrin (HPâCD) administered intravenously in patients with Niemann-Pick disease type C1
Molecular Genetics and Metabolism
Published February 2021 by Prof Alan Boyd
The Global Alliance for iPSC Therapies (GAiT)
Stem Cell Research
Published December 2020 by Dr Patrick Ginty
Regulatory Readiness Level: a Tool to Enhance Early Regulatory Adoption in Academic Discover
A Technological University Dublin Journal of Research and Innovation
Published December 2020 by Eamonn McGowran
Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial
The Lancet Oncology
Published November 2020 by Prof Alan Boyd
Advanced therapy regulation in the UK: what might the future hold post-Brexit?
Cell & Gene Therapy Insights
Published September 2020 by Dr Patrick Ginty
Procurement and Distribution of Study Medicines
Principles and Practice of Clinical Trials
Published March 2020 by Dr Eric Hardter
Evolution of the Development of Core Competencies in Pharmaceutical Medicine and Their Potential Use in Education and Training
Frontiers in Pharmacology
Published March 2020 by Prof Alan Boyd
Evolution of Ethical Principles in the Practice of Pharmaceutical Medicine From a UK Perspective
Frontiers in Pharmacology
Published January 2020 by Prof Alan Boyd
LB6. EDP-938, a Novel RSV N-Inhibitor, Administered Once or Twice Daily Was Safe and Demonstrated Robust Antiviral and Clinical Efficacy in a Healthy Volunteer Challenge Study
Open Forum Infectious Diseases
Published October 2019 by Dr Bryan Murray
902. A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of a Single Immunization of Ad26.RSV.preF against RSV Infection in a Viral Challenge Model in Healthy Adults
Open Forum Infectious Diseases
Published October 2019 by Dr Bryan Murray
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR
Nature Medicine
Published September 2019 by Kim Champion
Preclinical development of an automated injection device for intradermal delivery of a cell-based therapy
Drug Delivery and Translational Research
Published October 2017 by Dr Patrick Ginty
The Faculty of Pharmaceutical Medicine – Foundation, function and future
Journal of Medicines Development Sciences
Published August 2017 by Prof Alan Boyd
Intravesical rAd-IFNα/Syn3 for Patients With High-Grade, Bacillus Calmette-Guerin-Refractory or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase II Randomized Study
Journal of Clinical Oncology
Published August 2017 by Prof Alan Boyd
Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia
Original Article
Published January 2017 by Kim Champion
A Tool for Investigating Asthma and COPD Exacerbations: A Newly Manufactured and Well Characterised GMP Wild-Type Human Rhinovirus for Use in the Human Viral Challenge Model
PLOS ONE
Published December 2016 by Dr Bryan Murray
Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem TM ): Clinical evaluation of 11β-HSD1 inhibitor UE2343
British Journal of Pharmacology
Published December 2016 by Prof Alan Boyd
A Novel Second Generation CD19 CAR for Therapy of High Risk/Relapsed Paediatric CD19+ Acute Lymphoblastic Leukaemia and Other Haematological Malignancies: Preliminary Results from the Carpall Study
Published December 2016 by Kim Champion
Global Regulatory Perspective for MSCs
Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption
Published August 2016 by Dr Patrick Ginty
pH-sensitive pHLIP® coated niosomes
Molecular Membrane Biology
Published August 2016 by Monica Pianella
Cell & Gene Therapy Commercial Insight April 2016
Published July 2016 by Prof Alan Boyd
452. RegenVOX - Translational Exploitation Strategy for Stem Cell-Based Tissue-Engineered Laryngeal Implants Undergoing Phase I/II Clinical Trial
Cell Therapies II
Published May 2016 by Kim Champion
Planning an Academic Clinical Trial
Methods in Molecular Biology
Published May 2015 by Kim Champion
LATE-BREAKING ABSTRACT: Discovering new treatments for asthma and COPD. The use of the human viral challenge model with a newly manufactured and characterised GMP human rhinovirus
European Respiratory Journal
Published August 2015 by Dr Bryan Murray
The design and development of a novel automated intradermal delivery device for cell therapies
Cytotherapy
Published June 2015 by Dr Patrick Ginty
Evaluation of materials of biological origin used in the production of cell-based medicinal products
The British Standards Institution
Published April 2015 by Dr Patrick Ginty
Qualification of academic facilities for small-scale automated manufacture of autologous cell-based products
Regenerative Medicine
Published August 2014 by Dr Patrick Ginty
Manufacturing models permitting roll out/scale out of clinically led autologous cell therapies: regulatory and scientific challenges for comparability
Cytotherapy
Published August 2014 by Dr Patrick Ginty
Foscarnet in the management of cytomegalovirus infections in hematopoietic stem cell transplant patients
Expert Review of Anti-infective Therapy
Published November 2012 by Prof Alan Boyd
Standards can help bring cell therapy products to market
BioProcess International
Published April 2012 by Dr Patrick Ginty
Serum CD73 Activity, An Enzyme Involved In Endothelial Barrier Function, Increases Following FP-1201 Treatment Of ALI/ARDS Patients
American Thoracic Society 2011 International Conference
Published May 2011 by Prof Alan Boyd
Regenerative medicine, resource and regulation: lessons learned from the remedi project
Regenerative Medicine
Published March 2011 by Dr Patrick Ginty
Achieving reimbursement for regenerative medicine products in the USA
Regenerative Medicine
Published May 2010 by Dr Patrick Ginty
